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The Science of Pain and Addiction: Neurobiology, Neuroplasticity, and Ethics at the Bedside

December 14, 2025 No Comments

Buprenology – The Study of Buprenorphine in the Treatment of Addiction and Chronic Pain

December 14, 2025 No Comments

How Dr. Eric Kandel’s Sea Slug Research Supports Ketamine as a Treatment for Chronic Pain

When it comes to understanding the mechanics of chronic pain and how to effectively treat it, insights from neuroscience are crucial. One of the most

December 14, 2025 No Comments

Healing or Harming? The Biochemical Consequences of Controlled Substance Medications

November 18, 2025 No Comments

Beta-Arrestin-Mediated Downregulation of μ-Opioid and Dopamine Receptors: Implications for Tolerance, Opioid-Induced Hyperalgesia, and the Opponent Process in Addiction

Grace Willoughby, DO PGY-2North MS Medical Center Family Medicine Residency Center AbstractChronic activation of G protein-coupled receptors (GPCRs), particularly μ-opioid receptors (MORs) and dopamine

November 18, 2025 No Comments

Benzodiazepine-Induced Receptor Alterations and the Rebound Effect: A Neuroadaptive Model Aligned with Opponent Process Theory

Mackenzie Reilly, DOPGY2 Internal Medicine Residency – North Mississippi Medical CenterTupelo Mississippi Abstract Benzodiazepines, as positive allosteric modulators of the GABA-A receptor complex, exert powerful

November 18, 2025 No Comments

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The Science of Pain and Addiction: Neurobiology, Neuroplasticity, and Ethics at the Bedside

Buprenology – The Study of Buprenorphine in the Treatment of Addiction and Chronic Pain

How Dr. Eric Kandel’s Sea Slug Research Supports Ketamine as a Treatment for Chronic Pain

Healing or Harming? The Biochemical Consequences of Controlled Substance Medications

Beta-Arrestin-Mediated Downregulation of μ-Opioid and Dopamine Receptors: Implications for Tolerance, Opioid-Induced Hyperalgesia, and the Opponent Process in Addiction

Benzodiazepine-Induced Receptor Alterations and the Rebound Effect: A Neuroadaptive Model Aligned with Opponent Process Theory

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